p53 mutations in basal cell carcinomas.

Article

p53 mutations in basal cell carcinomas.

Cancer research - 1 Jul 1992

Rady P, Scinicariello F, Wagner R F, Tyring S K

Abstract excerpt

Genomic DNA from 14 basal cell carcinoma biopsies was screened for the presence of mutations in the p53 gene, using the polymerase chain reaction followed by direct DNA sequencing. Heterozygous mutations were detected in 7 of 14 (50%) samples investigated. All mutations were G:C-A:T transitions,...

Topics

Base Sequence
Carcinoma, Basal Cell
Genes, p53
Humans
Molecular Sequence Data
Mutation
Ultraviolet Rays

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