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Article

Persistent p53 mutations in single cells from normal human skin.

The American journal of pathology - 1 Oct 2001

Ling G, Persson A, Berne B, Uhlén M, Lundeberg J, Ponten F

Abstract excerpt

Epidermal clones of p53-mutated keratinocytes are abundant in chronically sun-exposed skin and may play an important role in early development of skin cancer. Advanced laser capture microdissection enables genetic analysis of targeted cells from tissue sections without contamination from neighboring cells. In this study p53 gene mutations were characterized in single cells from normal, chronically sun-exposed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11583952
DOI: 10.1016/S0002-9440(10)62511-4
PMCID: PMC1850504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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