Article
Two domains of yeast U6 small nuclear RNA required for both steps of nuclear precursor messenger RNA splicing.
Science (New York, N.Y.) - 19 Oct 1990
Fabrizio P, Abelson J
Abstract excerpt
U6 is one of the five small nuclear RNA's (snRNA's) that are required for splicing of nuclear precursor messenger RNA (pre-mRNA). The size and sequence of U6 RNA are conserved among organisms as diverse as yeast and man, and so it has been proposed that U6 RNA functions as a catalytic element in splicing. A procedure for in vitro reconstitution of functional yeast U6 small nuclear ribonucleoproteins (snRNP's)...
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