Phenotypic stability of B16-BL6 melanoma exposed to low levels of tyrosine and phenylalanine.

Article

Phenotypic stability of B16-BL6 melanoma exposed to low levels of tyrosine and phenylalanine.

Anticancer research - 1 Jan 2000

Elstad C A, Meadows G G

Abstract excerpt

We previously demonstrated that tyrosine (Tyr) and phenylalanine (Phe) restriction suppresses metastatic heterogeneity of B16-BL6 (BL6) melanoma and selects for tumor variants with decreased metastatic potential. In this study, we investigate stability of this Tyr- and Phe-modulated tumor phenoty...

Topics

Animals
Antineoplastic Agents
Cell Communication
Female
Lung Neoplasms
Melanoma, Experimental
Mice
Neoplasm Metastasis
Neoplasm Transplantation
Phenotype
Phenylalanine
Tumor Cells, Cultured
Tyrosine

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