Suppression of tumorigenic and metastatic potentials of human melanoma cell lines by mutated (143 Val-Ala) p53.

doi:10.1038/bjc.1998.369

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Article

Suppression of tumorigenic and metastatic potentials of human melanoma cell lines by mutated (143 Val-Ala) p53.

British journal of cancer - 1 Jun 1998

Rauth S, Green A, Kichina J, Shilkaitis A

Abstract excerpt

Metastatic melanoma, compared with other cancers, appears to be unusual because of its low frequency of p53 mutations and prevalence of wild-type p53 protein in advanced malignancy. Here, we examined the effects of wild-type and mutated p53 (143 Val-Ala) on tumorigenic and metastatic potential of...

Topics

Animals
Biocompatible Materials
Cell Division
Collagen
DNA, Neoplasm
Drug Combinations
Gene Expression
Genes, p53
Humans
Laminin
Liver Neoplasms, Experimental
Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Melanoma

Mice

Mice, Inbred BALB C

Mutation

Neoplasm Transplantation

Proteoglycans

Source

Open in PubMed Open full text

Identifiers

PMID: 9649136
DOI: 10.1038/bjc.1998.369
PMCID: PMC2150410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9649136-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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