Human tumor spontaneous metastasis in immunosuppressed newborn rats. II. Multiple selections of human melanoma metastatic clones and variants.

doi:10.1002/ijc.2910490520

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Human tumor spontaneous metastasis in immunosuppressed newborn rats. II. Multiple selections of human melanoma metastatic clones and variants.

International journal of cancer - 11 Nov 1991

Bailly M, Doré J F

Abstract excerpt

Using a recently developed model of human tumor spontaneous metastasis in immunosuppressed newborn rats, we selected variants with different metastatic abilities from the human melanoma cell line M4Be. We used 4 in vivo selection approaches, by direct serial tumor transplantations or by techniques involving in vitro reculture of the cells recovered from s.c. tumors or lung and lymph-node metastases. In addition,...

Topics

Animals
Animals, Newborn
Cell Separation
Genetic Variation
Humans
Immunosuppression Therapy
Lung Neoplasms
Lymph Nodes
Lymphatic Metastasis
Male
Melanoma, Experimental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Nude

Neoplasm Metastasis

Neoplasm Transplantation

Rats

Rats, Inbred Strains

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1937961
DOI: 10.1002/ijc.2910490520

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1937961-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human tumor spontaneous metastasis in immunosuppressed newborn rats. II. Multiple selections of human melanoma metastatic clones and variants.PMID 1937961Read ↗

Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma MetastasesSemantic proximity Read ↗

A new Mr 55,000 surface protein implicated in melanoma progression: association with a metastatic phenotype.Semantic proximity Read ↗

Cloned low metastatic variants from human lung carcinoma metastases.Semantic proximity Read ↗

Metastatic potential of human melanoma cells in nude mice--characterisation of phenotype, cytokine secretion and tumour-associated antigens.Semantic proximity Read ↗

Analyzing the metastatic phenotype.Semantic proximity Read ↗

Establishment of a human melanoma cell line lacking p53 expression and spontaneously metastasizing in nude mice.Semantic proximity Read ↗

Reduced tumor incidence, metastatic potential, and cytokine responsiveness of nm23-transfected melanoma cells.Semantic proximity Read ↗

CD44: physiological expression of distinct isoforms as evidence for organ-specific metastasis formation.Semantic proximity Read ↗

B16 melanoma variants selected by one or more cycles of spontaneous metastasis to the same organ fail to exhibit organ specificity.Semantic proximity Read ↗

Spontaneous lung metastases in a human lung tumor xenograft: a new experimental model.Semantic proximity Read ↗

[Metastatic phenotype of a substrain of human melanoma Mel-7 transplanted into various immunodeficient mice].Semantic proximity Read ↗

PERSPECTIVES ON CLASSIC ARTICLES: Metastasis Suppressor GenesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.