Article
Rapid genotyping of APOA5 -1131T>C polymorphism using high resolution melting analysis with unlabeled probes.
Gene - 1 May 2012
Liu Song-Mei, Xu Feng-Xia, Shen Fan, Xie Yan
Abstract excerpt
The APOA5 -1131 T/C polymorphism (rs662799) exhibits a very strong association with elevated TG levels in different racial groups. High resolution melting (HRM) analysis with the use of unlabeled probes has shown to be a convenient and reliable tool to genotyping, but not yet been used for detecting rs662799 polymorphism. We applied the unlabeled probe HRM analysis and direct DNA sequencing to assay the -1131T>C...
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