Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotyping cytomegalovirus UL97 mutations by high-resolution melting analysis with unlabeled probe.

Archives of virology - 1 Mar 2012

Zhao Xiao-Tao, Zhou Dan-Qiu, Wu Shuai, Chen Yue-Wen, Shao Yong, Zhang Jie, Xia Chang-Sheng, Wang Ke-Peng, Yang Hong, Wan Jun, Yu Bo, Zhang Zheng, Zhang Wei

Abstract excerpt

Human cytomegalovirus (CMV) is an opportunistic pathogen, and infections with this virus can be treated with ganciclovir (GCV). Most GCV-resistant clinical CMV isolates contain a mutation in the UL97 gene. Genotypic assays for diagnostic screening of GCV-resistant CMV have been developed. High-resolution melting analysis (HRMA) with unlabeled probe is considered a perfect tool for this purpose. In this study, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antiviral Agents
Share to Cytomegalovirus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

Share to Ganciclovir

Share to Molecular Typing

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Transition Temperature

Share to Virology

Source

Identifiers

PMID: 22205145
DOI: 10.1007/s00705-011-1173-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotyping cytomegalovirus UL97 mutations by high-resolution melting analysis with unlabeled probe.PMID 22205145Read ↗

Detection of Two Drug-Resistance Mutants of the Cytomegalovirus by High-Resolution Melting Analysis.Semantic proximity Read ↗

Unlabeled probes for the detection and typing of herpes simplex virus.Semantic proximity Read ↗

Sequencing of cytomegalovirus UL97 gene for genotypic antiviral resistance testing.Semantic proximity Read ↗

Genotypic characterization of human cytomegalovirus UL97 phosphotransferase natural polymorphism in the era of ganciclovir and maribavir.Semantic proximity Read ↗

Cytomegalovirus UL97 mutations in the era of ganciclovir and maribavirSemantic proximity Read ↗

Novel UL97 drug resistance mutations identified at baseline in a clinical trial of maribavir for resistant or refractory cytomegalovirus infectionSemantic proximity Read ↗

SNP genotyping by unlabeled probe melting analysis.Semantic proximity Read ↗

Rapid genotyping of APOA5 -1131T>C polymorphism using high resolution melting analysis with unlabeled probes.Semantic proximity Read ↗

Closed-tube genotyping with unlabeled oligonucleotide probes and a saturating DNA dye.Semantic proximity Read ↗

Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance.Semantic proximity Read ↗

Molecular Epidemiology of Cytomegalovirus UL97 and UL54 variants in Taiwan.Semantic proximity Read ↗

Characterization of aberrant melting peaks in unlabeled probe assays.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.