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Article

Generation and characterization of hD5 and C-terminal Mutant hD(5m) transgenic rats.

Brain research - 11 Apr 2012

Xu Zhiliang, Dong Suzhen, Du Dan, Jiang Nan, Sun Peiqua, Wang Huikun, Yin Liang, Zhang Xuliang, Cao Xiaohua, Zhen Xuechu, Hu Yinghe

Abstract excerpt

Dopamine D1-like receptors play important roles in many brain activities such as cognition and emotion. We have generated human hD5 and mutant human hD5 (hD(5m)) transgenic rats. The C-terminal juxtamembrane domain of mutant hD5 was identical to that of hD5 pseudogenes. The transgenes were driven by the CAMKII promoter that led the expression mainly in the cerebral cortex and hippocampus. We have used different...

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PMID: 22386496
DOI: 10.1016/j.brainres.2012.01.076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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