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Article

Regional and subtype selective changes of neurotransmitter receptor density in a rat transgenic for the Huntington's disease mutation.

Journal of neurochemistry - 1 Aug 2005

Bauer Andreas, Zilles Karl, Matusch Andreas, Holzmann Carsten, Riess Olaf, von Hörsten Stephan

Abstract excerpt

Huntington's disease (HD) is an autosomal dominantly inherited progressive neurodegenerative disorder caused by a CAG/polyglutamine repeat expansion in the gene encoding the huntingtin protein. We have recently generated a rat model transgenic for HD, which displays a slowly progressive phenotype resembling the human adult-onset type of disease. In this study we systematically assessed the distribution and...

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Identifiers

PMID: 16033418
DOI: 10.1111/j.1471-4159.2005.03169.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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