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Article

Probing the constitutive activity among dopamine D1 and D5 receptors and their mutants.

Methods in enzymology - 1 Jan 2010

Plouffe Bianca, D'Aoust Jean-Philippe, Laquerre Vincent, Liang Binhui, Tiberi Mario

Abstract excerpt

Dopamine D1 and D5 receptors are prototypical cell-surface seven-transmembrane (TM) G protein-coupled receptors (GPCRs) mediating elevation of intracellular cAMP levels. The high level of constitutive activity of D5 receptor mediating intracellular cAMP production is one of the functional hallmar...

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PMID: 21036239
DOI: 10.1016/B978-0-12-381298-8.00016-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21036239-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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