Article
DRD2 and ANKK1 gene polymorphisms and alcohol dependence: a case-control study among a Mendelian population of East Asian ancestry.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jan 2000
Suraj Singh Huidrom, Ghosh Pradeep Kumar, Saraswathy Kallur Nava
Abstract excerpt
AIMS: Dopamine receptors are extensively studied in association with alcohol dependence (AD), since they are thought to be the key neural substrate for alcohol and other drug-related reinforcement and reward behaviours. The present study aims to understand the role of dopamine receptors in susceptibility to AD with respect to three sites of DRD2 gene (-141C Ins/Del, TaqIB and TaqID) and TaqIA site of ANKK1 gene...
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