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Article

Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction.

The American journal of clinical nutrition - 1 Oct 2008

Allayee Hooman, Baylin Ana, Hartiala Jaana, Wijesuriya Hemani, Mehrabian Margarete, Lusis Aldons J, Campos Hannia

Abstract excerpt

BACKGROUND: 5-Lipoxygenase (5-LO) catalyzes the rate-limiting step of the biosynthesis of proinflammatory leukotrienes from arachidonic acid (AA) and has been associated with atherosclerosis in animal models and humans. We previously reported that variants of a 5-LO promoter repeat polymorphism were associated with carotid atherosclerosis in humans, an effect that was exacerbated by high dietary AA but mitigated...

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Share to Arachidonate 5-Lipoxygenase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18842779
DOI: 10.1093/ajcn/88.4.934
PMCID: PMC3014055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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