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Article

Impact of single-nucleotide polymorphisms at the TP53-binding and responsive promoter region of BCL2 gene in modulating the phenotypic variability of LGMD2C patients.

Molecular biology reports - 1 Jul 2012

Hadj Salem Ikhlass, Kamoun Fatma, Louhichi Nacim, Trigui Moez, Triki Chahnez, Fakhfakh Faiza

Abstract excerpt

Apoptosis of skeletal muscle fibers is a well-known event occurring in patients suffering from muscular dystrophies. In this study, we hypothesized that functional polymorphisms in genes involved in the mitochondrial apoptotic pathway might modulate the apoptotic capacity underlying the muscle lo...

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Share to bcl-2-Associated X Protein
Share to Genes, bcl-2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-bcl-2

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Source

Identifiers

PMID: 22367371
DOI: 10.1007/s11033-012-1581-4

Genes

BAX
BCL2
SGCG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22367371-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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