Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Effects of Polymorphisms of Death Pathway Genes and Mitochondrial Pathway Genes in Intervertebral Disc Degeneration.

Turkish neurosurgery - 1 Jan 2017

Eser Betul, Eser Olcay, Aslan Esra, Dolgun Habibullah

Abstract excerpt

AIM: It has been proposed that apoptosis is effective on intervertebral disc degeneration. This study is the first study in which both polymorphisms and expressions of apoptotic genes in patients with intervertebral disc degeneration (IVDD) are evaluated together. The aim of our study is to determine whether polymorphisms and expressions of apoptotic genes involved in both pathways are related with grades of IVDD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to bcl-2-Associated X Protein
Share to fas Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, bcl-2

Share to Intervertebral Disc

Share to Intervertebral Disc Degeneration

Share to Lumbar Vertebrae

Share to Mitochondria

Source

Identifiers

PMID: 27593829
DOI: 10.5137/1019-5149.JTN.17927-16.0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Effects of Polymorphisms of Death Pathway Genes and Mitochondrial Pathway Genes in Intervertebral Disc Degeneration.PMID 27593829Read ↗

Meta-Analysis of the Association Between FAS Ligand and TRAIL Genetic Polymorphisms and Intervertebral Disc Degeneration Susceptibility in Chinese Han population.Semantic proximity Read ↗

Correlation between Polymorphism of TRAIL Gene and Condition of Intervertebral Disc Degeneration.Semantic proximity Read ↗

Association of FAS and FAS ligand polymorphisms with the susceptibility and severity of lumbar disc degeneration in Chinese Han population.Semantic proximity Read ↗

TRAIL gene 1595C/T polymorphisms contribute to the susceptibility and severity of intervertebral disc degeneration: a data synthesis.Semantic proximity Read ↗

Significant association of TNF-α, but not other pro-inflammatory cytokines, single nucleotide polymorphisms with intervertebral disc degeneration in Iranian population.Semantic proximity Read ↗

Causes of and Molecular Targets for the Treatment of Intervertebral Disc Degeneration: A ReviewSemantic proximity Read ↗

Association of BCL-2 polymorphism with the presence and severity of lumbar disc degeneration in the Chinese Han population.Semantic proximity Read ↗

Molecular mechanisms of cell death in intervertebral disc degeneration (Review)Semantic proximity Read ↗

Single-nucleotide gene polymorphisms involving cell death pathways: a study of Chinese patients with lumbar disc herniation.Semantic proximity Read ↗

5:52137. Mitochondrial involvement in Fas-mediated apoptosis of human lumbar disc cellsSemantic proximity Read ↗

Association of interleukin 2, interleukin 12, and interferon-γ with intervertebral disc degeneration in Iranian populationSemantic proximity Read ↗

Association between Fas/FasL gene polymorphism and musculoskeletal degenerative diseases: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.