Article
Association of BCL-2 polymorphism with the presence and severity of lumbar disc degeneration in the Chinese Han population.
Clinical laboratory - 1 Jan 2012
Shang Xiao-Peng, Sun Xue-Cheng, Wang Yu-Xu, Ju Bin-Bin
Abstract excerpt
BACKGROUND: Apoptosis is involved in the mechanism of lumbar disc disease (LDD). BCL-2 has been shown to play an anti-apoptosis role. The present study aims to examine the association of -938C > A polymorphism of the BCL-2 gene with the presence and severity of LDD in the Chinese Han population. METHODS: This study consisted of 325 patients with LDD and 236 normal controls. The grade of disc degeneration was...
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