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Article

BCL2 genotypes: functional and neurobehavioral outcomes after severe traumatic brain injury.

Journal of neurotrauma - 1 Aug 2010

Hoh Nicole Zangrilli, Wagner Amy K, Alexander Sheila A, Clark Robert B, Beers Sue R, Okonkwo David O, Ren Dianxu, Conley Yvette P

Abstract excerpt

Traumatic brain injury (TBI) triggers a cascade of apoptotic-related events that include BCL2 expression, a pro-survival protein in the apoptosis pathway. The purpose of this study was to use tagging single nucleotide polymorphism (tSNP) genotypes to screen the BCL2 gene to determine if genetic variability in the BCL2 gene influences outcomes in 205 patients with severe TBI. Outcomes (Glasgow Outcome Scale [GOS],...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20504155
DOI: 10.1089/neu.2009.1256
PMCID: PMC2967822

Genes

BCL2

Provenance

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