Article
Association of genetic polymorphisms of glutamate decarboxylase 2 and the dopamine D2 receptor with obesity in Taiwanese subjects.
Annals of Saudi medicine - 1 Jan 2000
Chen Ke-Chang, Lin Yi-Chen, Chao Wen-Chii, Chung Hsieh-Kun, Chi Su-Sheng, Liu Wen-Sheng, Wu Wen-Tung
Abstract excerpt
BACKGROUND AND OBJECTIVES: It has been proposed that glutamate decarboxylase 2 and the dopamine D2 receptor are involved in the brain reward cascade to increase carbohydrate craving and cause eating disorders. We investigated the association between the polymorphisms of the GAD2 and DRD2 genes and obesity with a higher body mass index (BMI) in Taiwanese patients. DESIGN AND SETTING: A retrospective, case-control...
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