Article
Childhood obesity and the role of dopamine D2 receptor and cannabinoid receptor-1 gene polymorphisms.
Genetic testing and molecular biomarkers - 1 Dec 2012
Col Araz Nilgun, Nacak Muradiye, Oguzkan Balci Sibel, Benlier Necla, Araz Mustafa, Pehlivan Sacide, Balat Ayse, Aynacioglu A Sukru
Abstract excerpt
AIMS: The dopaminergic and endocannabinoid systems are involved in regulation of feeding behavior. The aim of the study is to examine the possible relation between polymorphisms of the dopamine D2 receptor (DRD2) and cannabinoid receptor-1 (CNR1) genes and childhood obesity. METHODS: A hundred obese children and 100 healthy controls were analyzed for DRD2 Taq1A and Taq1B and CNR1 1359G/A polymorphisms. Genotyping...
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