Relationship between serum GAD-Ab and the genetic polymorphisms of GAD2 and type 2 diabetes mellitus.

doi:10.4238/2015.April.10.10

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Article

Relationship between serum GAD-Ab and the genetic polymorphisms of GAD2 and type 2 diabetes mellitus.

Genetics and molecular research : GMR - 10 Apr 2015

Li Q, Qiao Z R, Liu D B, Zeng J T, Zhang J, Bo Y, Zu H Y, Hu Q, Wu X, Dong S S

Abstract excerpt

In this study, we investigated the relationship between serum glutamic acid decarboxylase (GAD) autoantibody (Ab) levels and single nucleotide polymorphisms (SNPs) of the glutamic acid de-carboxylase 2 (GAD2) 5'-untranslated region and the susceptibility to type 2 diabetes in the Han population. The distributions of patients with SNPs in the GAD2 5'-untranslated region (rs2236418, rs185649317, and rs8190590) and...

Topics

Aged
Autoantibodies
Case-Control Studies
Diabetes Mellitus, Type 2
Female
Gene Frequency
Genetic Predisposition to Disease
Glutamate Decarboxylase
Humans
Male
Middle Aged
Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 25966064
DOI: 10.4238/2015.April.10.10

Genes

GAD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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