Article
Dopamine D2 receptor gene variants: association and linkage studies in impulsive-addictive-compulsive behaviour.
Pharmacogenetics - 1 Jun 1995
Blum K, Sheridan P J, Wood R C, Braverman E R, Chen T J, Comings D E
Abstract excerpt
Drug and alcohol seeking behaviour has become a great global problem affecting millions of inhabitants with a cost to society in the billions. Dopaminergic reward pathways have frequently been implicated in the etiology of addictive behaviour. While other neurotransmitters have also been implicated, to date the only molecular genetic defect which has been found to associate with alcoholism, drug dependency,...
Topics
- Behavior, Addictive
- Compulsive Behavior
- Genetic Linkage
- Genetic Variation
- Humans
- Impulsive Behavior
- Mental Disorders
- Obesity
- Receptors, Dopamine D2