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Article

Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study.

BMC medical genetics - 11 Feb 2010

Prasad Pushplata, Ambekar Atul, Vaswani Meera

Abstract excerpt

BACKGROUND: Dopamine is an important neurotransmitter involved in reward mechanism in the brain and thereby influences development and relapse of alcohol dependence. The dopamine D2 receptor (DRD2) gene on chromosome 11 (q22-q23) has been found to be associated with increased alcohol consumption through mechanisms involving incentive salience attributions and craving in alcoholic patients. Therefore, we...

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Identifiers

PMID: 20146828
DOI: 10.1186/1471-2350-11-24
PMCID: PMC2829542

Genes

DRD2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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