Article
NFE2L2 gene variants and susceptibility to childhood-onset asthma.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion - 1 Jan 2000
Córdova Emilio J, Jiménez-Morales Silvia, Centeno Federico, Martinez-Hernández Angélica, Martínez-Aguilar Nora, Del-Río-Navarro Blanca E, Gómez-Vera Javier, Orozco Lorena
Abstract excerpt
INTRODUCTION: Environmental factors causing oxidative stress are known to be associated with asthma morbidity. The antioxidative gene NFE2L2 has been implicated in asthma development in mice models. In humans, the SNPs -617C/A and -653G/A, located at the promoter region of NFE2L2 gene, have been...
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