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Article

Second-hand smoke and NFE2L2 genotype interaction increases paediatric asthma risk and severity.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jun 2021

Johansson Elisabet, Martin Lisa J, He Hua, Chen Xiaoting, Weirauch Matthew T, Kroner John W, Khurana Hershey Gurjit K, Biagini Jocelyn M

Abstract excerpt

BACKGROUND: Second-hand smoke (SHS) exposure is associated with paediatric asthma, and oxidative stress is believed to play a role in mediating this association. The nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) is important for the defence against oxidative stress. OBJECTIVE: To explore interactions between NFE2L2 genotype and SHS exposure in paediatric asthma risk. METHODS: We used a genotyped subset of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33382170
DOI: 10.1111/cea.13815
PMCID: PMC9248014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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