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Article

Genetic variation in S-nitrosoglutathione reductase (GSNOR) and childhood asthma.

The Journal of allergy and clinical immunology - 1 Aug 2007

Wu Hao, Romieu Isabelle, Sienra-Monge Juan-Jose, Estela Del Rio-Navarro Blanca, Anderson Daniel M, Jenchura Charlotte A, Li Huiling, Ramirez-Aguilar Matiana, Del Carmen Lara-Sanchez Irma, London Stephanie J

Abstract excerpt

BACKGROUND: S-nitrosothiols are potent endogenous bronchodilators depleted in asthmatic airway lining fluid. S-nitrosoglutathione reductase (GSNOR; also known as alcohol dehydrogenase 5 or formaldehyde dehydrogenase) catalyzes the metabolism of S-nitrosoglutathione (GSNO) and controls intracellular levels of S-nitrosothiols. GSNOR knockout mice have increased lung S-nitrosothiol levels and are therefore protected...

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Source

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Identifiers

PMID: 17543375
DOI: 10.1016/j.jaci.2007.04.022
PMCID: PMC2094003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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