Article
Atopic dermatitis: Interaction between genetic variants of GSTP1, TNF, TLR2, and TLR4 and air pollution in early life.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Sept 2018
Hüls Anke, Klümper Claudia, MacIntyre Elaina A, Brauer Michael, Melén Erik, Bauer Mario, Berdel Dietrich, Bergström Anna, Brunekreef Bert, Chan-Yeung Moira, Fuertes Elaine, Gehring Ulrike, Gref Anna, Heinrich Joachim, Standl Marie, Lehmann Irina, Kerkhof Marjan, Koppelman Gerard H, Kozyrskyj Anita L, Pershagen Göran, Carlsten Christopher, Krämer Ursula, Schikowski Tamara
Abstract excerpt
BACKGROUND: Associations between traffic-related air pollution (TRAP) and childhood atopic dermatitis (AD) remain inconsistent, possibly due to unexplored gene-environment interactions. The aim of this study was to examine whether a potential effect of TRAP on AD prevalence in children is modified by selected single nucleotide polymorphisms (SNPs) related to oxidative stress and inflammation. METHODS:...
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