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Article

Genome-wide essential gene identification in Streptococcus sanguinis.

Scientific reports - 1 Jan 2011

Xu Ping, Ge Xiuchun, Chen Lei, Wang Xiaojing, Dou Yuetan, Xu Jerry Z, Patel Jenishkumar R, Stone Victoria, Trinh My, Evans Karra, Kitten Todd, Bonchev Danail, Buck Gregory A

Abstract excerpt

A clear perception of gene essentiality in bacterial pathogens is pivotal for identifying drug targets to combat emergence of new pathogens and antibiotic-resistant bacteria, for synthetic biology, and for understanding the origins of life. We have constructed a comprehensive set of deletion mutants and systematically identified a clearly defined set of essential genes for Streptococcus sanguinis. Our results...

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Share to Bacillus subtilis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22355642
DOI: 10.1038/srep00125
PMCID: PMC3216606

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