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Article

Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange.

Molecular and cellular biology - 1 May 2012

Muñoz-Galván Sandra, Tous Cristina, Blanco Miguel G, Schwartz Erin K, Ehmsen Kirk T, West Stephen C, Heyer Wolf-Dietrich, Aguilera Andrés

Abstract excerpt

Most spontaneous DNA double-strand breaks (DSBs) arise during replication and are repaired by homologous recombination (HR) with the sister chromatid. Many proteins participate in HR, but it is often difficult to determine their in vivo functions due to the existence of alternative pathways. Here we take advantage of an in vivo assay to assess repair of a specific replication-born DSB by sister chromatid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22354996
DOI: 10.1128/MCB.00111-12
PMCID: PMC3347241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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