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Article

Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development

21 Feb 2012

Abstract excerpt

The Notch signaling pathway has emerged as an important regulator of endochondral bone formation. Although recent studies have examined the role of Notch in mesenchymal and chondro-osteo progenitor cell populations, there has yet to be a true examination of Notch signaling specifically within developing and committed chondrocytes, or a determination of whether cartilage and bone formation are regulated via...

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PMID: 22354840
DOI: 10.1242/dev.070649

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