Article
Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2010
Tao Jianning, Chen Shan, Yang Tao, Dawson Brian, Munivez Elda, Bertin Terry, Lee Brendan
Abstract excerpt
Osteosclerosis is a pathologic bone disease characterized by an increase in bone formation over bone resorption. Genetic factors that contribute to the pathogenesis of this disease are poorly understood. Dysregulation or mutation in many components of the Notch signaling pathway results in a wide...
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