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Article

RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells.

Proceedings of the National Academy of Sciences of the United States of America - 13 Mar 2007

Vasyutina Elena, Lenhard Diana C, Wende Hagen, Erdmann Bettina, Epstein Jonathan A, Birchmeier Carmen

Abstract excerpt

In the developing muscle, a pool of myogenic progenitor cells is formed and maintained. These resident progenitors provide a source of cells for muscle growth in development and generate satellite cells in the perinatal period. By the use of conditional mutagenesis in mice, we demonstrate here that the major mediator of Notch signaling, the transcription factor RBP-J, is essential to maintain this pool of...

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Share to Cell Proliferation
Share to Immunoglobulin J Recombination Signal Sequence-Binding Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Satellite Cells, Skeletal Muscle

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Identifiers

PMID: 17360543
DOI: 10.1073/pnas.0610647104
PMCID: PMC1815471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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