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Article

Double-strand break-induced targeted mutagenesis in plants.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012

Lyznik L Alexander, Djukanovic Vesna, Yang Meizhu, Jones Spencer

Abstract excerpt

Double-strand breaks are very potent inducers of DNA recombination. There is no recombination between DNA molecules unless one or two DNA strands are broken. It has become feasible to introduce double-strand breaks at specific chromosomal loci by using dedicated, redesigned endonucleases with altered DNA-binding specificities. Such breaks are mainly repaired by error-prone nonhomologous recombination pathways in...

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Identifiers

PMID: 22351025
DOI: 10.1007/978-1-61779-558-9_32

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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