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Article

Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways.

Genome research - 1 Mar 2013

Qi Yiping, Zhang Yong, Zhang Feng, Baller Joshua A, Cleland Spencer C, Ryu Yungil, Starker Colby G, Voytas Daniel F

Abstract excerpt

Improved methods for engineering sequence-specific nucleases, including zinc finger nucleases (ZFNs) and TAL effector nucleases (TALENs), have made it possible to precisely modify plant genomes. However, the success of genome modification is largely dependent on the intrinsic activity of the engineered nucleases. In this study, we sought to enhance ZFN-mediated targeted mutagenesis and gene targeting (GT) in...

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Identifiers

PMID: 23282329
DOI: 10.1101/gr.145557.112
PMCID: PMC3589543

Genes

LIG4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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