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Article

Wnt and BMP signals control intestinal adenoma cell fates.

International journal of cancer - 15 Nov 2012

Farrall Alexandra L, Riemer Pamela, Leushacke Marc, Sreekumar Amulya, Grimm Christina, Herrmann Bernhard G, Morkel Markus

Abstract excerpt

Cellular hierarchies and signals that govern stemness and differentiation of intestinal adenoma cells are not well defined. In this study, we used organotypic culture to investigate the impact of β-catenin and BMP signals in cells that form intestinal adenoma in the mouse. We found that activatio...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22344573
DOI: 10.1002/ijc.27500

Genes

APC
BMP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22344573-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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