Article
Patient-calibrated agent-based modelling of ductal carcinoma in situ (DCIS): from microscopic measurements to macroscopic predictions of clinical progression.
Journal of theoretical biology - 21 May 2012
Macklin Paul, Edgerton Mary E, Thompson Alastair M, Cristini Vittorio
Abstract excerpt
Ductal carcinoma in situ (DCIS)--a significant precursor to invasive breast cancer--is typically diagnosed as microcalcifications in mammograms. However, the effective use of mammograms and other patient data to plan treatment has been restricted by our limited understanding of DCIS growth and ca...
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