Article
Examining the pathogenesis of breast cancer using a novel agent-based model of mammary ductal epithelium dynamics.
PloS one - 1 Jan 2013
Chapa Joaquin, Bourgo Ryan J, Greene Geoffrey L, Kulkarni Swati, An Gary
Abstract excerpt
The study of the pathogenesis of breast cancer is challenged by the long time-course of the disease process and the multi-factorial nature of generating oncogenic insults. The characterization of the longitudinal pathogenesis of malignant transformation from baseline normal breast duct epithelial dynamics may provide vital insight into the cascading systems failure that leads to breast cancer. To this end,...
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