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Article

PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems.

PLoS computational biology - 1 Feb 2018

Ghaffarizadeh Ahmadreza, Heiland Randy, Friedman Samuel H, Mumenthaler Shannon M, Macklin Paul

Abstract excerpt

Many multicellular systems problems can only be understood by studying how cells move, grow, divide, interact, and die. Tissue-scale dynamics emerge from systems of many interacting cells as they respond to and influence their microenvironment. The ideal "virtual laboratory" for such multicellular systems simulates both the biochemical microenvironment (the "stage") and many mechanically and biochemically...

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Identifiers

PMID: 29474446
DOI: 10.1371/journal.pcbi.1005991
PMCID: PMC5841829

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