Article

Growth Dynamics of Ductal Carcinoma in Situ Recapitulate Normal Breast Development

2023-10-02

Abstract excerpt

<h4>ABSTRACT</h4> Ductal carcinoma in situ (DCIS) and invasive breast cancer share many morphologic, proteomic, and genomic alterations. Yet in contrast to invasive cancer, many DCIS tumors do not progress and may remain indolent over decades. To better understand the heterogenous nature of this disease, we reconstructed the growth dynamics of 18 DCIS tumors based on the geo-spatial distribution of their somatic...

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Literature Corpus work: 53e73af5-80fa-59e5-b7af-85c65cb772bf
DOI: 10.1101/2023.10.01.560370

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