The mcm17 mutation of yeast shows a size-dependent segregational defect of a mini-chromosome.

doi:10.1007/s002940050264

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Article

The mcm17 mutation of yeast shows a size-dependent segregational defect of a mini-chromosome.

Current genetics - 1 Sept 1997

Roy N, Poddar A, Lohia A, Sinha P

Abstract excerpt

Mini-chromosome-maintenance (mcm) mutants were described earlier as yeast mutants which could not stably maintain mini-chromosomes. Out of these, the ARS-specific class has been more extensively studied and is found to lose chromosomes and mini-chromosomes due to a defect in the initiation of DNA...

Topics

Cell Cycle Proteins
Chromosome Deletion
Chromosomes, Fungal
Cloning, Molecular
DNA Replication
Fungal Proteins
Genes, Fungal
Mutation
Restriction Mapping
Saccharomyces cerevisiae Proteins

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