Article
The mcm17 mutation of yeast shows a size-dependent segregational defect of a mini-chromosome.
Current genetics - 1 Sept 1997
Roy N, Poddar A, Lohia A, Sinha P
Abstract excerpt
Mini-chromosome-maintenance (mcm) mutants were described earlier as yeast mutants which could not stably maintain mini-chromosomes. Out of these, the ARS-specific class has been more extensively studied and is found to lose chromosomes and mini-chromosomes due to a defect in the initiation of DNA replication at yeast ARSs. In the present study we have identified a number of mcm mutants which show size-dependent...
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