Article
MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3.
EMBO reports - 1 Feb 2001
Takei Y, Swietlik M, Tanoue A, Tsujimoto G, Kouzarides T, Laskey R
Abstract excerpt
The MCM proteins are essential for the initiation of DNA replication. We have isolated an MCM3-associated protein (MCM3AP) in a two-hybrid screen using MCM3. Here we demonstrate that MCM3AP is an acetyltransferase which acetylates MCM3 and that chromatin-bound MCM3 is acetylated in vivo. The MCM3...
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