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Article

Pegylated interferon-α induced hypoferremia is associated with the immediate response to treatment in hepatitis C.

Hepatology (Baltimore, Md.) - 1 Aug 2012

Ryan John D, Altamura Sandro, Devitt Emma, Mullins Sarah, Lawless Matthew W, Muckenthaler Martina U, Crowe John

Abstract excerpt

UNLABELLED: Pegylated interferon-α (PEG-IFN-α) forms an integral part of the current treatment for hepatitis C virus (HCV) infection. PEG-IFN-α suppresses HCV production by augmenting the innate antiviral immune response. Recent studies have reported the induction of hepcidin, the iron regulatory hormone, by IFN-α in vitro. As hepcidin plays an important role in innate immunity, we hypothesized that this finding...

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PMID: 22334511
DOI: 10.1002/hep.25666

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STAT3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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