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Article

Influence of genes suppressing interferon effects in peripheral blood mononuclear cells during triple antiviral therapy for chronic hepatitis C.

PloS one - 1 Jan 2015

Iijima Sayuki, Matsuura Kentaro, Watanabe Tsunamasa, Onomoto Koji, Fujita Takashi, Ito Kyoko, Iio Etsuko, Miyaki Tomokatsu, Fujiwara Kei, Shinkai Noboru, Kusakabe Atsunori, Endo Mio, Nojiri Shunsuke, Joh Takashi, Tanaka Yasuhito

Abstract excerpt

The levels of expression of interferon-stimulated genes (ISGs) in liver are associated with response to treatment with pegylated interferon (PEG-IFN) plus ribavirin (RBV). However, associations between the responses of ISGs to IFN-based therapy and treatment efficacy or interleukin-28B (IL28B) genotype have not yet been determined. Therefore, we investigated the early responses of ISGs and interferon-lambdas...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25706116
DOI: 10.1371/journal.pone.0118000
PMCID: PMC4338062

Genes

SOCS1
SOCS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of genes suppressing interferon effects in peripheral blood mononuclear cells during triple antiviral therapy for chronic hepatitis C.PMID 25706116Read ↗

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