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Modulation of hepatitis C virus replication by iron and hepcidin in Huh7 hepatocytes

19 May 2011

Abstract excerpt

Several clinical observations point to an intricate crosstalk between iron (Fe) metabolism and chronic hepatitis C virus (HCV) infection. In this study, we wanted to investigate the molecular control that Fe levels exert on HCV replication at the hepatocyte level. In keeping with previous observations we confirmed that supra-physiological intracellular Fe induced by haemin treatment down-modulated HCV replication...

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Share to Erythropoietin and Anemia Treatment
Share to Hemoglobinopathies and Related Disorders
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PMID: 21593278
DOI: 10.1099/vir.0.032706-0

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