Article
The SWI/SNF chromatin remodeling complex exerts both negative and positive control over LET-23/EGFR-dependent vulval induction in Caenorhabditis elegans.
Developmental biology - 1 Jul 2016
Flibotte Stephane, Kim Bo Ram, Van de Laar Emily, Brown Louise, Moghal Nadeem
Abstract excerpt
Signaling by the epidermal growth factor receptor (EGFR) generates diverse developmental patterns. This requires precise control over the location and intensity of signaling. Elucidation of these regulatory mechanisms is important for understanding development and disease pathogenesis. In Caenorh...
Topics
- Amino Acid Sequence
- Animals
- Animals, Genetically Modified
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Cycle Proteins
- Chromatin Assembly and Disassembly
- Embryonic Induction
- ErbB Receptors
- Female
- Hermaphroditic Organisms
- Male
- Multiprotein Complexes
- Mutation
- Polymorphism, Single Nucleotide
- Recombinant Fusion Proteins
- Signal Transduction
- Species Specificity