Article
The SWI/SNF chromatin remodeling complex exerts both negative and positive control over LET-23/EGFR-dependent vulval induction in Caenorhabditis elegans.
Developmental biology - 1 Jul 2016
Flibotte Stephane, Kim Bo Ram, Van de Laar Emily, Brown Louise, Moghal Nadeem
Abstract excerpt
Signaling by the epidermal growth factor receptor (EGFR) generates diverse developmental patterns. This requires precise control over the location and intensity of signaling. Elucidation of these regulatory mechanisms is important for understanding development and disease pathogenesis. In Caenorhabditis elegans, LIN-3/EGF induces vulval formation in the mid-body, which requires LET-23/EGFR activation only in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.