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Article

Re-evaluation of the Big Blue® mouse assay of propiconazole suggests lack of mutagenicity.

Environmental and molecular mutagenesis - 1 Jan 2012

Shane Barbara S, Zeiger Errol, Piegorsch Walter W, Booth Ewan D, Goodman Jay I, Peffer Richard C

Abstract excerpt

Propiconazole (PPZ) is a conazole fungicide that is not mutagenic, clastogenic, or DNA damaging in standard in vitro and in vivo genetic toxicity tests for gene mutations, chromosome aberrations, DNA damage, and cell transformation. However, it was demonstrated to be a male mouse liver carcinogen...

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PMID: 22329022
DOI: 10.1002/em.20689

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22329022-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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