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Article

Organ-targeted mutagenicity of nitrofurantoin in Big Blue transgenic mice.

Mutagenesis - 1 Sept 2006

Quillardet Philippe, Arrault Xavier, Michel Valérie, Touati Eliette

Abstract excerpt

Nitrofurans are widely used in human medicine, as nitrofurantoin and nifuroxazide, still prescribed for long-term antimicrobial prophylaxis of urinary tract and gastrointestinal infection in humans respectively. Recent experiments in mammals, as well as reports mentioning toxic effects in humans associated with a long-term use, specially in the case of nitrofurantoin, raised the need for reevaluating their...

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Identifiers

PMID: 16895946
DOI: 10.1093/mutage/gel036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Organ-targeted mutagenicity of nitrofurantoin in Big Blue transgenic mice.PMID 16895946Read ↗

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