Article
Analysis of the mutations induced by conazole fungicides in vivo.
Mutagenesis - 1 May 2010
Ross Jeffrey A, Leavitt Sharon A
Abstract excerpt
The mouse liver tumorigenic conazole fungicides triadimefon and propiconazole have previously been shown to be in vivo mouse liver mutagens in the Big Blue transgenic mutation assay when administered in feed at tumorigenic doses, whereas the non-tumorigenic conazole myclobutanil was not mutagenic. DNA sequencing of the mutants recovered from each treatment group as well as from animals receiving control diet was...
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