Integration of toxicological approaches with "omic" and related technologies to elucidate mechanisms of carcinogenic action: propiconazole, an example.

Abstract excerpt

The field of mechanistic chemical carcinogenesis has evolved with the advent and advances in genomic, proteomic and metabolomic technologies. These advances allow mechanistic events along the process of exposure to frank tumors to be studied in great detail. Herein is reviewed an example of this approach using, propiconazole, a triazole-containing antifungal agent that is a mouse hepatocarcinogen. This review...

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