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Article

Development of the lip and palate: FGF signalling.

Frontiers of oral biology - 1 Jan 2012

Stanier Philip, Pauws Erwin

Abstract excerpt

The fibroblast growth factor (FGF) signalling pathway is critically involved in several aspects of craniofacial development, including formation of the lip and the palate. FGF receptors are activated by extracellular FGF ligands in order to regulate cellular processes such as migration and morphogenesis through instruction of specific target gene expression. A key factor in the development of orofacial structures...

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Topics

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Share to Cleft Lip
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibroblast Growth Factors

Share to Gene Expression Regulation, Developmental

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Share to Receptors, Fibroblast Growth Factor

Source

Identifiers

PMID: 22759671
DOI: 10.1159/000337618

Genes

FGF8
FGFR1
FGFR2
SHH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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