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Article

MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1

1 May 2020

Abstract excerpt

BACKGROUND: Due to the lack of research on the pathological mechanism of temporomandibular joint osteoarthritis (TMJOA), there are few effective treatment measures in the clinic. In recent years, microRNAs (miRs) have been demonstrated to play an important role in the pathogenesis of osteoarthritis (OA) by regulating a variety of target genes, and the latest evidence shows that miR-21-5p is specifically...

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PMID: 32357909
DOI: 10.1186/s13075-020-2145-y

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